My guess for the 2022 OD roster would be something like this.
C: Rutschman
1B: Mountcastle
2B: Jones
3B: Urias
SS: Mateo
LF: Hays
CF: Mullins
RF: Santander
DH: Mancini
Bench: Gutierrez, McKenna, Ciuffo/Veteran Backup, Martin/Veteran UI
SP: Means, Veteran Free Agent, Zimmermann, Akin, Baumann/Lowther/A. Wells/Bradish/Ellis
RP: T. Wells, Lopez, Scott, Tate, Sulser, Harvey (if healthy)/Krihbel, Ellis, long reliever that loses out on the fifth spot.
I think Rutschman makes the OD roster, but if the CBA doesn't make major changes to the eligibility system, I could see the Orioles doing the same thing they did in 2009 with Wieters and Zaun and Rutschman is up in May.