So much this, and I say it just as a boxscore observer born in the 1970's.
The line even can please the 21st Century DIPS connoiseur, never mind that it was the team's 1st WS game ever as massive underdogs to the '63/'65 champs going for their 3rd championship in 4 years.
I think it is clearly Drabowsky and nothing else is too close.
In my personal memory, Boddicker Game 2 after Hoyt beat us in the first of a 5-game ALCS stands out the most.
....and every other MLB team.
Baltimore Orioles: Erik Bedard (July 7, 2007, versus Rangers)
Pitching line: 9 IP, 2 H 0 R, 0 BB, 15 SO (Game Score: 98)
Remember that one awesome season for Bedard? He led the AL in fewest hits per nine innings in 2007 and most K's per nine and had a day to remember in Arlington, a tough park to rack up a big game. The Orioles cashed in and traded him to the Mariners after the season for Adam Jones and Chris Tillman, and Bedard had trouble staying healthy after that.
For argument's sake: Mike Mussina matched Bedard's 98 with a one-hit, 15-strikeout game in 2000, walking two batters. The highest extra-inning score belongs to Jerry Walker, who spun a 16-inning shutout in 1959 for a 111. He was only 20 and had started the All-Star Game that year; perhaps not coincidentally he came down with arm problems in 1960. He did have a long career as an executive with the Tigers, Cardinals and Reds.
Most likely to beat it: Grayson Rodriguez is the team's top pitching prospect. He averaged less than five innings per start in Low-A, so he's a long ways away, but he is a strikeout machine.
Notable: Here's an example of how the game has changed. Jim Palmer won three Cy Young Awards, threw 211 complete games and tossed 53 shutouts, but had just 13 double-digit strikeout games in his career -- and in just one of those 13 did he allow zero runs. His best nine-inning Game Score was 90.
Palmer didn't need to strike out everyone with the defenses he typically had behind him. I guess this is going by game score only, though.
I would have been impressed had they mentioned Drabowsky in the '66 World Series. I don't know if that really counts as the best pitching performance in the history of the franchise but it's in the conversation.
I do remember this game by Bedard. I think there was a lot of consternation on here about whether or not he could go a full 9 innings, like if that was going to determine if he was a true ace or not. He was so much fun to watch that year. His curveball was amazing.