This lineup frustrates me because you are taking a good defender and putting them at DH, and putting a bad defender in the field. I also think it's problematic for Henderson's development to be playing him at DH often, and it speaks to Hyde's distrust of young players in general, and specifically on defense.
That said, if this is Hyde's "a" lineup (in his mind) then Henderson should be getting reps in RF, so that at least you can put Henderson somewhere in the field and take out Santander (since he clearly feels like Urias and Fraier are the better IF defenders)